Mixed cryoglobulinaemia after hepatitis C virus: more and less ambiguity.
نویسنده
چکیده
منابع مشابه
The cryoglobulinaemias.
Cryoglobulins are immunoglobulins that precipitate in vitro at temperatures less than 37°C and produce organ damage through two main pathways: vascular sludging (hyperviscosity syndrome, mainly in type I cryoglobulinaemia) and immune-mediated mechanisms (principally vasculitis, in mixed cryoglobulinaemia). Cryoglobulinaemia is associated with many illnesses, which can be broadly grouped into in...
متن کاملHepatitis C virus infection with peripheral neuropathy is not always associated with cryoglobulinaemia.
OBJECTIVES To describe cases of peripheral neuropathy associated with chronic hepatitis C virus infection without mixed cryoglobulinaemia. METHODS Four cases of peripheral neuropathy associated with chronic hepatitis C virus infection with persistent negativity of mixed cryoglobulinaemia were found. RESULTS All patients had small increases of transaminase levels and a positive viraemia. Liv...
متن کاملPeripheral neuropathy associated with essential mixed cryoglobulinaemia: a role for hepatitis C virus infection?
BACKGROUND The prevalence of hepatitis C virus (HCV) infection has been estimated at 43 to 84% in patients with essential mixed cryoglobulinaemia in recent large series. Some of these cases have been successfully treated with interferon-alpha. The objective was to evaluate the prevalence and the possible role of HCV infection in essential mixed cryoglobulinaemia. METHODS Fifteen patients (eig...
متن کاملPolyarteritis nodosa and mixed cryoglobulinaemia related to hepatitis B and C virus coinfection.
OBJECTIVE To determine the responsibility of hepatitis B virus (HBV) and hepatitis C virus (HCV) and therapeutic implications in a patient who developed systemic vasculitis. CASE REPORT The case of a 38 year old woman who had a past history of addiction to intravenous drugs and developed systemic vasculitis after infection by HBV and HCV is described. The clinical and laboratory findings subs...
متن کاملRituximab for the treatment of glomerulonephritis in hepatitis C associated cryoglobulinaemia.
Mixed-type cryoglobulins are strongly associated with hepatitis C virus (HCV) infection and may lead to vasculitis with renal involvement. The treatment of this condition is antiviral therapy for HCV, but this may be ineffective or not tolerated because of side effects. Alternative strategies such as immunosuppressive drugs and plasmapheresis are of limited use, especially in patients after liv...
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ورودعنوان ژورنال:
- Annals of the rheumatic diseases
دوره 57 12 شماره
صفحات -
تاریخ انتشار 1998